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6. VU University Medical Center, Amsterdam:
The research program of the Verweij group concentrates on the premise to uncover biological pathways that play a crucial role in chronic inflammatory autoimmune diseases. Therefore, we apply a functional genomics approach using transcriptomics and proteomics technology to detect the biological pathways that are disturbed. Central in our research program is the activation of the innate immune system. Since this system is also intimately linked to inflammatory and modulatory processes, many human diseases result from an aberrant innate immunity, either primary or secondary. Within our group we have several lines of research ongoing, focusing on I. Regulation of innate immunity (A. A functional genomics approach to search for genetically determined interindividual differences in innate immunity. B. Allele-Specific regulation of cytokine gene expression.) and, II. A functional genomics approach to study the molecular pathogenesis of chronic inflammatory diseases.
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