Publications

Publications at partner 1-6, 7-9, 10-12

10 BIOXELL S.p.A., Milano

1) Panina P, Mariani M, D'Ambrosio D. Chemokine receptors in chronic obstructive pulmonary disease (COPD). Curr Drug Targets. 2006 Jun;7(6):669-74.
2) Sironi M, Martinez FO, D'Ambrosio D, Gattorno M, Polentarutti N, Locati M, Gregorio A, Iellem A, Cassatella MA, Van Damme J, Sozzani S, Martini A, Sinigaglia F, Vecchi A, Mantovani A. Differential regulation of chemokine production by Fc{gamma} receptor engagement in human monocytes: association of CCL1 with a distinct form of M2 monocyte activation (M2b, Type 2). J Leukoc Biol. 2006 May.
3) Benigni F, Baroni E, Zecevic M, Zvara P, Streng T, Hedlund P, Colli E, D'Ambrosio D, Andersson KE. Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis.
BJU Int. 2006 Mar;97(3):617-24.
4) D'Ambrosio D. Regulatory T cells: how do they find their space in the immunological arena?
Semin Cancer Biol. 2006 Apr;16(2):91-7.
5) D'Ambrosio D. Targeting chemoattractant receptors in allergic inflammation.
Curr Drug Targets Inflamm Allergy. 2005 Apr;4(2):163-7.
6) Piccio L, Rossi B, Colantonio L, Grenningloh R, Gho A, Ottoboni L, Homeister JW, Scarpini E, Martinello M, Laudanna C, D'Ambrosio D, Lowe JB, Constantin G. Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII.
J Immunol. 2005 May 1;174(9):5805-13.

11 Institute of Molecular Biotechnology of the Austrian Academy of Science, Vienna

1. Alnaeeli M, Penninger JM, Teng YT. Immune interactions with CD4+ T cells promote the development of functional osteoclasts from murine CD11c+ dendritic cells. J Immunol. 2006 Sep 1;177(5):3314-26. PMID: 16920972
2. Atfield, A. D., Liu, P., and Penninger, J. M. (2006). The biochemical mechanisms of T-cell anergy. Curr. Immunol. Rev. 2, 73-99.
3. Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, Morony S, Rubin E, Sarao R, Hojilla CV, Komnenovic V, Kong YY, Schreiber M, Dixon SJ, Sims SM, Khokha R, Wada T, Penninger JM. Regulation of cancer cell migration and bone metastasis by RANKL.Nature. 2006 Mar 30;440(7084):692-6. PMID: 16572175 
4. Marty RR, Dirnhofer S, Mauermann N, Schweikert S, Akira S, Hunziker L, Penninger JM, Eriksson U. MyD88 signaling controls autoimmune myocarditis induction.Circulation. 2006 Jan 17;113(2):258-65. Epub 2006 Jan 9. PMID: 16401773 
5. Maruyama K, Takada Y, Ray N, Kishimoto Y, Penninger JM, Yasuda H, Matsuo K. Receptor Activator of NF-{kappa}B Ligand and Osteoprotegerin Regulate Proinflammatory Cytokine Production in Mice. J Immunol. 2006 Sep 15;177(6):3799-805.
PMID: 16951341
6. Nakashima T, and Josef M. Penninger. Chemotactic regulation of cancer cell migration and bone metastases by RANKL." Experimental Medicine 24, 1777-1780. 2006.
7. Pospisilik, J. A., Knauf, C., Joza, N., Cani, P. D., Nakashima, T., Sarao, R., Neely, G., Kahn, C. R., Burcelin, R., and Josef M. Penninger.  Targeted reduction in muscle oxidative phosphorylation enhances insulin-sensitivity and prevents diabetes and obesity in mice. submitted. 2006.
8. Roy AA, Nunn C, Ming H, Zou MX, Penninger J, Kirshenbaum LA, Dixon SJ, Chidiac P. Upregulation of endogenous RGS2 mediates cross-desensitization between Gs and Gq signaling in osteoblasts. J Biol Chem. 2006 Sep 1; [Epub ahead of print] PMID: 16950788
9. Wada T, Nakashima T, Hiroshi N, Penninger JM. RANKL-RANK signaling in osteoclastogenesis and bone disease.Trends Mol Med. 2006 Jan;12(1):17-25. Epub 2005 Dec 13. Review. PMID: 16356770  .
10. Krawczyk, C. M., Jones, R. G., Atfield, A., Bachmaier, K., Arya, S., Odermatt, B., Ohashi, P. S., and Penninger, J. M. (2005). Differential control of CD28-regulated in vivo immunity by the E3 ligase Cbl-b. J. Immunol. 174, 1472-8.
11. Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Bao, L., Zhang, B., Huang, L., Liu, G., Wang, Z., Liu, Y., Zheng, D., Slutsky, A. S., Wada, T., Liu, D., Qin, C., Jiang, C., and Penninger, J. M. (2005). A critical role of angiotensin converting enzyme 2 (ACE2) in SARS pathogenesis. Nature Medicine, 11, 875-9.
12. Liu, Y. C., Penninger, J., and Karin, M. (2005). Immunity by ubiquitylation: a reversible process of modification. Nat. Rev. Immunol. 5, 941-52.
13. Mahamed, D. A., Marleau, A., Alnaeeli, M., Singh, B., Zang, X., Penninger, J. M., and Teng, Y. T. (2005). G(-) anaerobes reactive CD4+ T cells trigger RANKL mediated enhanced alveolar bone loss in diabetic NOD mice. Diabetes 54, 1477-84.
14. Rangachari, M., Eriksson, U., Vollmann, E. H., and Penninger, J. M. (2005). A novel model for pathogenesis of autoimmune heart failure: the role of dendritic cells. International Congress Series (Uehara Foundation Review) 1285, 192-201.
15. Wada, T., Nakashima, T., Oliveira-dos-Santos, A. J., Gasser, J., Hara, H., Schett, G., and Penninger, J. M. (2005). The molecular scaffold Gab2 is a crucial component of RANK signaling and osteoclastogenesis. Nature Med. 11, 394-9.

12 Institute of Rheumatology Warsaw

1. Maslinski W., Kontny E. Komentarz. Przewlekle choroby zapalne stawów. Medycyna po Dyplomie, luty 2005, vol. 14, nr 2.
2. Zarebska Z., Zielinska J., Zhukov I., Maslinski W. Apoptosis induced by membrane damage in human lymphocytes, effects of arachidonic acid and its photoproducts. Acta Biochim Pol. 2005, 52(1), 179-94.
3. Marcinkiewicz J., Mak M., Bobek M., Biedron R., Bialecka A., Koprowski M., Kontny E., Maslinski W. Is there a role of taurine bromamine in inflammation? Interactive effects with nitrite and hydrogen peroxide. Inflamm. Res., 2005, Jan54(1), 42-49.
4. Jackiewicz E., Szczepanska-Sadowska E., Maslinski W. Expression of mineralocorticoid receptors mRNA in the brain, heart and kidney of Spraque Dawley rats with renovascular hypertension. Brain Res Bull, 2005, Feb15, 65(1), 23-29.
5. Marotte H., Maslinski W., Miossec P. Circulating tumour necrosis factor-alpha bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response. Arthritis Res Ther., 2005, 7(1), R149-55, Epub 2004 Dec 1.
6. Kontny E., Maslinski W. Rola zjawisk komórkowych (Rozdz.2: Patogeneza chorób reumatycznych), Ksiazka pt. Zapalne choroby reumatyczne w wieku rozwojowym, Wyd. Lekarskie PZWL, Warszawa 2005, wydanie I, 16-29.
7. Kontny E., Chorazy-Massalska M., Rudnicka W., Marcinkiewicz J., Maslinski W. Cytotoxicity of taurine metabolites depends on the cell type. Adv in Exp Med & Biol, 2006, Vol.583, 157-171.
8. Warnawin E., Burakowski T., Gajewski M., Kornatka A., Rudnicka W., Michalak C., Maldyk P., Maslinski S., Maslinski W. Ponowne dojrzewanie odróznicowanych w hodowlach in vitro chondrocytów w warunkach obnizonego stezenia tlenu. (Low oxygen tension promotes redifferentiation of dedifferentiated human articular chondrocytes in vitro). Reumatologia, 2006, 44,2.
9. Gajewski M., Warnawin E., Gajewska J., Sygitowicz G., Rell-Bakalarska M., Burakowski T., Dziewczopolski W., Szczepanik Sz., Wysocki L., Pachecka J., Maslinski W., Maslinski S. Badania nad mechanizmem toksycznego oddzialywania neutrofilów na chondrocyty hodowane w róznych stezeniach tlenu. (Experimental study of the to cytotoxic effects of neutrophils on chondrocytes cultivated in different oxygen concentrations).  Reumatologia, 2006, 44,2, 76-86.
10. Chorazy-Massalska M., Kontny E., Maslinski W. Naturalne komórki regulatorowe (CD4+CD25+). [Natural regulatory T cells (CD4+CD25+)].  Postepy Biologii Komórki, 2006, 33, 1, 71-80.
11. Kontny E., Maslinski W. Limfocyty B - funkcje fizjologiczne i udzial w patogenezie reumatoidalnego zapalenia stawów. (B lymphocytes - the physiological role and implication in the pathogenesis of rheumatoid arthritis). Reumatologia, 2006, 44, 3, 150-161.
12. Kontny E., Rudnicka W., Chorazy-Massalska M., Marcinkiewicz J., Maslinski W. Taurine chloramine inhibits proliferation of rheumatoid arthritis synoviocytes by triggering a p53-dependent pathway. Inflamm. Res. 55, 2006, 446-455, DOI 10.1007/s00011-006-5067-5.
13. Kontny E., Chorazy-Massalska M., Rudnicka W., Marcinkiewicz J., Maslinski W. Comparison of taurine chloramine and taurine bromamine effects on rheumatoid arthritis synoviocytes. Amino Acids, 2006, DOI 10.1007/s00726-006-0368-0.